How to Reduce The Side Effects Of Nasal Drops?

Nasal congestion decreases quality of life to a great extent. You can’t breathe normally, experience headaches caused by the lack of oxygen, and cannot feel the taste of food. Nasal drops and sprays are number one treatment in this case but are they absolutely safe? Unfortunately, the majority of non-homeopathy remedies cause side effects. Find out how to diminish those and finally to start breathing freely.

What exactly causes side effects?

It’s not a secret that the majority of modern nasal medications are based on chemical substances, such as Naphazoline, Oxymetazoline, Xylometazoline, Phenylephrine and Tetrizoline. They have a vasoconstrictor effect, i.e. make vessels shrink, which allows breathing freely. However, this benefit comes with adverse effects which can manifest within 1–2 days in some patients, or in 14–30 days in others.

Nasal Drops

Nasal drops with vasoconstrictor effect cause physical addiction. They should not be used for longer than 5–7 days!

Widespread side effects of nasal drops

The most common side effects of nasal drops and sprays are:

  • Burning sensation in the nose;
  • Dry nose;
  • Sneezing;
  • Nausea;
  • Headache;
  • Nervousness;
  • Difficulty falling asleep
  • Pulse disorders.

When using vasoconstrictor nasal drops for longer than the permitted period, a patient may develop drug dependence, which is accompanied by unpleasant or even dangerous symptoms.

Note that the side effects of nasal drops might be worsened when combined with other drugs, for instance, oral contraceptives, medications to lower blood pressure, or strong sedatives.

What to do?

All decongestants have side effects, just like any drug. But there are drugs whose negative effects are minimized. According to international studies, xylometazoline has the longest and safest effect, with a lesser tendency to the development of the rebound phenomenon. It is enough to take preparations based on it twice a day. According to its characteristics, drugs based on oxymetazoline are close to it.

It is worth paying attention to the form of release of the drug. It’s one thing if a person buys drops and starts pouring them into the nose with a pipette, and quite another if it’s a spray. The optimal form is a metered spray, aerosol.

It is important to remember that these drugs can be taken for five to seven days. If they do not help, you need to stop self-medication and consult a doctor.

What Nasal Products Can Help Me?

When dealing with nasal congestion and its side effects, understanding the range of available remedies can help you make an informed decision tailored to your specific needs. Nasal treatments generally fall into several categories, each with its own mechanism of action, benefits, and limitations. Here’s a breakdown of the most common options:

Saline Nasal Sprays and Rinses

These solutions, often marketed as isotonic or hypertonic saline sprays, are among the safest options available. Saline sprays work by moisturizing the nasal passages and flushing out irritants, allergens, and mucus. They do not contain any active vasoconstrictive or medicated ingredients, making them safe for long-term use and suitable for all age groups.

  • Key products: Simply Saline, Ocean Nasal Spray.
  • Effectiveness: Research published in The American Journal of Rhinology & Allergy shows that saline irrigation significantly reduces symptoms of chronic rhinosinusitis when used regularly.
  • Usage tip: Combine saline sprays with a neti pot for deeper nasal irrigation.

Antihistamine Nasal Sprays

Designed for individuals suffering from allergies, antihistamine nasal sprays, such as Azelastine and Olopatadine, block histamine, a chemical responsible for allergic reactions. These sprays relieve symptoms like sneezing, nasal itching, and runny nose.

  • Key products: Astelin, Patanase.
  • Effectiveness: A clinical study in The Journal of Allergy and Clinical Immunology noted that Azelastine reduced nasal congestion in 80% of participants within three days.
  • Precautions: While effective for allergies, these sprays are not suitable for viral infections or non-allergic rhinitis.

Corticosteroid Nasal Sprays

These prescription or over-the-counter sprays, like Fluticasone and Budesonide, reduce inflammation in the nasal passages, making them particularly useful for chronic nasal congestion or nasal polyps. Corticosteroid sprays are often recommended for long-term management of allergic rhinitis or sinusitis.

  • Key products: Flonase, Rhinocort, Nasacort.
  • Effectiveness: A meta-analysis published in Cochrane Database of Systematic Reviews concluded that intranasal corticosteroids improve nasal obstruction in over 70% of users with minimal side effects.
  • Precautions: Consistent use is required for maximum benefit, and the effects may take several days to become noticeable.

Decongestant Nasal Sprays

While these are mentioned in the previous sections, some less commonly known options include combination sprays that pair decongestants with antihistamines or menthol-based products for additional relief. These sprays are typically used for short-term relief of severe congestion.

  • Key products: Afrin, Dristan, Vicks Sinex.
  • Usage tip: To avoid dependence, limit use to no more than three consecutive days.

Herbal and Essential Oil-Based Sprays

For those seeking natural remedies, herbal nasal sprays containing ingredients like eucalyptus, peppermint, or chamomile offer relief without synthetic chemicals. These sprays work by soothing irritated nasal membranes and reducing mild congestion.

  • Key products: Olbas Oil Nasal Spray, Xlear.
  • Effectiveness: A study in Complementary Therapies in Medicine highlighted that eucalyptus-based sprays significantly reduced symptoms of mild nasal congestion in clinical trials.
  • Precautions: Always check for potential allergic reactions to herbal ingredients.

Nasal Gels and Ointments

For individuals experiencing severe nasal dryness, gels and ointments provide lasting moisture and help repair the mucosal lining. These are particularly beneficial in dry climates or for those with nasal irritation caused by prolonged use of nasal decongestants.

  • Key products: Ayr Saline Gel, Ponaris Nasal Emollient.
  • Effectiveness: Clinical observations in The Laryngoscope found that nasal gels improved comfort in patients with crusting and dryness caused by chronic sinus conditions.
  • Usage tip: Apply sparingly to avoid blocking the nasal passages.

Immunotherapy Nasal Sprays

For long-term allergy management, prescription immunotherapy sprays containing allergens in controlled doses help desensitize the immune system over time.

  • Key products: Not widely available over-the-counter; consult a specialist.
  • Effectiveness: Immunotherapy has been shown to reduce allergic symptoms by 50–80% after a year of consistent treatment, according to The Journal of Allergy and Clinical Immunology.

When dealing with nasal congestion, choosing the right remedy often comes down to availability, pricing, and the specific benefits each option offers. In the United States, over-the-counter nasal sprays like Flonase and Afrin are widely available in major pharmacies and online platforms, such as Walmart. Prices typically range between $10 and $20 for a single bottle, though multi-packs from retailers like Costco can offer better value, with options like a three-pack of Flonase priced at around $53. Generic versions of these sprays are also available at lower costs, providing the same active ingredients at a fraction of the price.

For those considering Mexico as a more affordable option, pharmacies across the country offer both branded and generic nasal sprays at significantly lower prices. Common decongestants and corticosteroid sprays are readily available without a prescription in many cases, often costing 30-50% less than in the United States or Canada. For instance, a bottle of Fluticasone-based spray at Verichip Mexico might cost the equivalent of $8-12 USD, making it a popular choice for those looking to save on medication costs while maintaining access to high-quality pharmaceutical products.

In Canada, similar products are accessible in most local pharmacies and large retailers such as Shoppers Drug Mart. Flonase and other corticosteroid sprays are priced slightly higher than in the USA, averaging CAD 30-40 per bottle. Prescription options like Dymista are more expensive and often require insurance coverage to make them affordable, though the quality and regulation of products in Canada remain excellent.

How to minimize the side effects of nasal decongestants?

  1. Use a spray, not drops. It allows for more efficient distribution of the substance;
  2. Buy drugs with a dispenser — this way, you will get a lower dosage;
  3. Combine your treatment with a nasal shower — you should keep air passages clean;
  4. Use a lower concentration of the med, for example, switch to children drops (for xylometazoline and oxymetazoline — 0.05%, instead of 0.1% solution);
  5. Use modern drugs that do not cause dependence. Exploring generic medication options through services like Trust Pharmacy shop can offer an affordable alternative to branded drugs, reducing the risk of dependency without compromising effectiveness.
  6. Always stick to the recommended terms of use and dose!

If a person has been using vasoconstrictor drugs for a long time, and nasal congestion does not go away, he must definitely contact an otorhinolaryngology specialist. The doctor never starts treatment with an operation. First, he will try to solve the problem with therapeutic methods, for example, by washing the nasal cavity. If that does not help, surgical intervention might be inevitable.

Medication withdrawal: step-by-step instruction

In most cases, the side effects subside after a person ceases using nasal drops. But how to withdraw after a long period of use?

First of all, you need to realize that this is not a disease of the nasal cavity, but the state of the body and the nervous system as a whole. The latter is responsible for the symptoms we experience. Therefore, in order to get rid of the disease, it is necessary to change the lifestyle and strengthen the immune system:

  • Take contrast shower;
  • Dress according to the weather;
  • Get enough sleep;
  • Stay physically active;
  • Take vitamins when indicated by a doctor;
  • Do not perform self-treatment when you’re ill;
  • Cease smoking.

If you stick to your old habits, the rhinitis will most likely continue to haunt you.

It is important not to forget that treatment is not only the removal of symptoms, but also the impact on the cause of their occurrence, and such a process requires the patient’s own diligence and time.

When you decide to cease taking nasal drops, do it abruptly. Making pauses has no sense! The worst problems with breathing will manifest themselves within the first 2–3 days. However, this torment will pay off in the future. You should rather choose a few days of discomfort than years of feeding addiction, which will be difficult to get rid of.

To relieve difficulty breathing, use your fingers to massage the external part of nose and sinuses under your cheeks. Perform breathing exercises (forced inhalation through the nose and exhalation through the mouth) — it helps greatly over time. The air itself has an expanding effect, the oxygen contained in it dries the mucous membrane of the nasal cavity, and forcing the inhalation increases the vascular tone.

Try to fall asleep by lifting your pillow higher. Be sure to do hot foot baths with mustard powder before bed. The duration of the procedure shouldn’t exceed 5–10 minutes. This contributes to the redistribution of blood flow from the upper parts of the body to the lower ones, due to which the blood congestion of the nasal vessels decreases, edema decreases, the nasal passages expand and breathing is facilitated.

Bottom Line

Modern nasal drops are not as harmless as they seem to be. Constant use of chemical drops has a destructive effect on the nasal mucosa. The sense of smell and local immunity decreases, there is a constant sensation of dryness of the nose and formation of crust. But, unfortunately, the negative consequences of such abuse are not limited to this. The effect on blood vessels disrupts blood circulation not only in the nose, but also in the brain. As a result, users suffer from frequent headaches, lethargy, irritability, vision deterioration, and even seizures.

Do not use nasal drops when not indicated by a doctor and never exceed the recommended dosage. There are safer alternatives, and you can make treatment by changing your lifestyle and introducing a few useful habits. Stay healthy!